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Evidence to Improve Care

Guidance Documents

On occasion, we create guidance documents meant for clinicians or the general public that are separate from our health technology assessments and quality standards.

Lyme Disease


Ontario Health, in collaboration with Public Health Ontario, clinical experts, patients, and caregivers from across the province, has developed a clinical guidance document addressing the diagnosis and treatment of early localized Lyme disease.

Click below to learn more.

Clinical Guidance

If you are a health care professional: learn about management and investigation of early localized Lyme disease, based on the best available evidence (updated in 2024)

If you are a community pharmacist: learn about the assessment and prescribing of appropriate antibiotic prophylaxis to prevent Lyme disease following a tick bite using guidance for community pharmacists developed by Public Health Ontario, in collaboration with Ontario Health.

To learn more about Lyme disease, visit:

For more information, contact

Illustration of a tick

Ontario Health thanks the following individuals for their generous, voluntary contributions of time and expertise to help create this guidance document (credentials at the time of initial development in 2018):

Shoshanah Éliane Charlotte Deaton
Family Physician and Investigating Coroner
Clarence-Rockland Family Health Team

Kayleigh Hagerman
Physician, Emergency Medicine
Niagara Health System

Linda Kelso
Lived Experience Advisor as a Caregiver
Co-founder of the Ontario Lyme Alliance

Donna LaPointe
Primary Health Care Nurse Practitioner
Leamington and Area Family Health Team

Colin Lee
Public Health and Preventive Medicine
Associate Medical Officer of Health
Simcoe Muskoka District Health Unit

Kieran Moore
Public Health and Preventive Medicine
Queen's University

Bonnie Myslik
Primary Health Care Nurse Practitioner
Leamington and Area Family Health Team

Doug Sider
Public Health Preventive Medicine
Public Health Ontario

John F. Thompson
Lived Experience Advisor

Valerie Winberg
Primary Health Care Nurse Practitioner, Wound Care Specialist
Executive Director Twin Bridges Nurse Practitioner-Led Clinic

Heather Wise
Pharmacist and Patient Advisor
Pharmacy Department, Kingston General Hospital

For more information, contact

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