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Evidence to Improve Care

Portable Normothermic Cardiac Perfusion System in Donation After Cardiocirculatory Death


Final Recommendation

  • The Quality business unit at Ontario Health, based on guidance from the Ontario Health Technology Advisory Committee, recommends publicly funding portable normothermic cardiac perfusion systems for use in heart transplant following donation after cardiocirculatory death, conditional on Health Canada approval

Read the final recommendation report

For people who have heart failure at its most advanced stage, a heart transplant is the most effective treatment. However, there is a chronic shortage of hearts available for transplant.

A technology called a portable normothermic cardiac perfusion system may expand which donors are eligible to donate hearts, making more available.

This health technology assessment looked at the safety and effectiveness of this new technology for transporting hearts donated after cardiocirculatory death (when the donor’s heart has stopped beating and there is no longer blood flow or a pulse). The report considers whether the technology is cost-effective, the budget impact of publicly funding the technology, as well as the experiences, preferences and values of people waiting for a heart transplant, people who have received one, and family members of organ donors.

Read the full Health Technology Assessment report for more information.

Portable Normothermic Cardiac Perfusion System in Donation After Cardiocirculatory Death: A Health Technology Assessment (PDF)
March 2020

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The Ministry of Health is currently reviewing this recommendation.

The Ministry of Health has provided the following response: The Ministry has a standardized process in place to review health technology assessments and funding recommendations. This takes into consideration Ministry priorities, implementation options, the need for consultation with impacted stakeholders, and funding considerations.


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