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Evidence to Improve Care

Repetitive Transcranial Magnetic Stimulation for People With Treatment-Resistant Depression

Final Recommendation

  • Ontario Health, based on guidance from the Ontario Health Technology Advisory Committee, recommends publicly funding repetitive transcranial magnetic stimulation for people with treatment-resistant depression

Read the final recommendation report


Major depression is one of the most often diagnosed mental illnesses in Canada. People with major depression often have feelings of sadness, irritability, and hopelessness that do not go away, and find it hard to take pleasure in most activities.

Generally, people can be successfully treated with antidepressants, psychotherapy, or both. However, some people with major depression do not respond to these treatments. If people are diagnosed with treatment-resistant depression, other treatments can be tried. Repetitive transcranial magnetic stimulation is a noninvasive treatment that delivers magnetic pulses to stimulate the area of the brain associated with mood regulation.

This health technology assessment looked at how safe, effective, and cost-effective repetitive transcranial magnetic stimulation is for people with treatment-resistant depression. It also looked at the budget impact of publicly funding this treatment. And it looked at the experiences, preferences, and values of people with treatment-resistant depression.

Read the full health technology assessment report for more information.

The Ministry of Health is currently reviewing this recommendation.

The Ministry of Health has provided the following response: The Ministry has a standardized process in place to review health technology assessments and funding recommendations. This takes into consideration Ministry priorities, implementation options, the need for consultation with impacted stakeholders, and funding considerations.



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