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Evidence to Improve Care

Wire-Free, Nonradioactive Localization Techniques to Guide Surgical Excision of Nonpalpable Breast Tumours

    Status: Final recommendation

Final Recommendation

  • Ontario Health, based on guidance from the Ontario Health Technology Advisory Committee, recommends publicly funding wire-free, nonradioactive localization techniques for the localization of nonpalpable breast tumours.

Read the final recommendation report


The standard treatment for nonpalpable breast tumours is to surgically remove them. But because these tumours are so small, it is necessary to pinpoint their location before surgery by implanting a marker inside the tumour using mammogram or ultrasound guidance. This procedure is called localization.

The current localization techniques used in Ontario are wire-guided localization and radioactive seed localization, both of which have some limitations. Wire-free, nonradioactive localization is a new type of localization that overcomes these limitations. Two types are now being used at some hospitals in Ontario: magnetic seed localization and reflector-guided localization.

This health technology assessment looked at how safe and effective wire-free, nonradioactive localization techniques to guide surgical removal of nonpalpable breast tumours are. It also looked at the budget impact of publicly funding wire-free, nonradioactive localization techniques and at the experiences, preferences, and values of people who have undergone a localization procedure for the excision of a nonpalpable breast tumour.

Read the full health technology assessment report for more information.

Wire-Free, Nonradioactive Localization Techniques to Guide Surgical Excision of Nonpalpable Breast Tumours: A Health Technology Assessment
May 2023

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The Ministry of Health endorses this recommendation.

The Ministry of Health has provided the following response: The Ministry has a standardized process in place to review health technology assessments and funding recommendations. This takes into consideration Ministry priorities, implementation options, the need for consultation with impacted stakeholders, and funding considerations.



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