A health technology assessment was conducted on vertebroplasty reviewing the results of all randomized controlled trials published since 2005. The objective was to assess the efficacy and safety of this procedure in the treatment of painful osteoporotic vertebral compression fractures.
Recently, the results of two blinded randomized placebo-controlled trials of percutaneous vertebroplasty were reported. These trials, providing the highest quality of evidence available to date, do not support the use of vertebroplasty in patients with painful osteoporotic vertebral compression fractures. Based on the results of these trials, vertebroplasty confers no additional benefit over usual care and is not free of risks.
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Find out about the use of percutaneous verebroplasty in Ontario in the Ontario Health Technology Maps Project.
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